Dr. Manisha Shukla, a dedicated researcher with over 10 years of experience in the fields of bioscience and biotechnology. My career has been deeply rooted in exploring innovative scientific solutions, especially through my work with esteemed government research divisions like the Defense Research and Development Organization (DRDO).
About Me
Currently, I am serving as an Assistant Professor at Pandit S.N. Shukla University in Shahdol, Madhya Pradesh, where I am committed to inspiring and guiding students in their journey through the sciences. I completed my PhD from the prestigious IIT Roorkee, a journey that further strengthened my passion for research and innovation. My academic foundation includes a Bachelor’s and Master’s degree from the National Institute of Technology (NIT).
I also qualified for the Graduate Aptitude Test in Engineering (GATE), which opened doors to enriching research opportunities.
Research and Publications
With a research portfolio that includes 26 published papers and presentations at 7 international conferences, I have been fortunate to contribute to the advancement of bioscience and biotechnology. My work spans various aspects of these fields, aimed at addressing real-world challenges and improving scientific understanding.
Book Chapters
- Manisha Shukla*, Brajkishore Prajapati and Yadunath Pathak. A New Tool for Healthier Future of India. ICAR 2023, Recent Advances in Agriculture Sciences and Technology. ISBN-978-93- 91995-07-2.
Research Publications (SCI/SCIE JOURNALS)
- Shukla M and Narayan M. “Proteostasis and Its Role in Disease Development.” Cell biochemistry and biophysics, 18 Oct. 2024. doi: 10.1007/s12013-024-01581-6.
- Shukla M and Ahad MA. Balancing Act: Navigating the Intricacies of Proteostasis. Int J Res Med Sci 2024; 12:3091-9.
- Shukla M, Singh R, Chandley P and Rohatgi S (2024) Molecular cloning, expression, and purification, along with in silico epitope analysis of recombinant enolase proteins (a potential vaccine candidate) from Candida albicans and Candida auris. Front. Fungal Biol. 5:1399546. doi: 10.3389/ffunb.2024.1399546.
- Anjali Tomar, Deepak Bharati, Samrah Rehan, Rohit Kumar Vishwakarma and Manisha Shukla. 2024. The Quantitative Assessment of Bacterial Species from Soil Samples through Real Time PCR. Int.J.Curr.Microbiol.App.Sci. 13(6): 141-147. doi: https://doi.org/10.20546/ijcmas.2024.1306.015
- Kahkasha Parveen, Deepak Bharati, Samrah Rehan, Rohit Kumar Vishwakarma and Manisha Shukla. 2024. The Molecular Characterization of Antibiotic Resistant Genes Carrying Bacterial Species in Food Samples. Int.J.Curr.Microbiol.App.Sci. 13(6): 134-140. doi: https://doi.org/10.20546/ijcmas.2024.1306.014
- Ramashish Kushwaha, Rohit Kumar Vishwakarma, Manisha Shukla. Analysis of Serum Lipid Profile in Benign Prostatic Hyperplasia Patients and Control Subjects. International Journal of Research in Medical and Clinical Sciences. 2024;2(1): 114-118.
- Ankita Verma, Ramashish Kushwaha, Rohit Kumar Vishwakarma and Manisha Shukla. Comparative Analysis of Malondialdehyde Levels and Ferric Reducing Ability of Plasma in Pregnant and Non-Pregnant Women. Am J Biomed Sci & Res. 2024 22(5) AJBSR.MS.ID.003002, DOI: 10.34297/AJBSR.2024.22.003002.
- Manisha Shukla, Samrah Rehan, Rohit Kumar Vishwakarma, Anjali Tomar, Kahkasha Parveen. Recent Advances In Application Of Zinc Oxide Nanoparticals. 2024 IJCRT Volume 12, Issue 4 April 2024 ISSN: 2320-2882.
- Shradha Jhariya, Pappi Jaiswal, Pooja Mallah, Prachi Mishra, Ram Shankar, Pramod Kumar Pandey, Kaushalendra Kumar and Manisha Shukla. Assessing physical and chemical parameters of the Sone River in Madhya Pradesh, India. International Journal of Chemical Studies 2024; 12(3): 47-51.
- Akshita Shrivastava, Sonali Shrivastava, Jagrati Chaturvedi, Samrah Rehan, Manisha Shukla. Assessment of physical and chemical parameters of the Murna river: Spatial variation in water quality across different sampling sites. International Journal of Advanced Science and Research, Volume 9, Issue 1, 2024, Page No. 13-18.
- Manisha Shukla, Shilpi Mishra, Anjali Singh Maravi, Pradeep Kumar Rana and Rohit Kumar Vishwakarma. Assessing agricultural potential and environmental sustainability through quantification of soil macronutrients. International journal of applied research, 2024, vol 10 (5), 349-353.
- Mohammad Abdul Ahad, Pratiksha Mishra, Akankasha Tiwari, Pradeep Kumar Rana, Manisha Shukla. “EVALUATION OF SOIL FERTILITY STATUS IN A TRIBAL AREA OF SHAHDOL DISTRICT”. 2024. ISSN: 2456-3315. Vol.9, Issue 6, page no.241 – 244, June-2024.
- Abhishek Soni, Aditi Tiwari, Shalini Chaudhary and Manisha Shukla (June 2024). Studies of Physicochemical and Bacteriological Characteristics of Drinking Water Quality in Shahdol University. International Journal of Current Microbiology and Applied Sciences (IJCMAS) ISSN: 2319-7692(Print); 2319-7706 (Online), Volume-13, Issue-6.
- Harshita Mishra and Manisha Shukla (June 2024). Analyzing river water quality in Shahdol: A comprehensive assessment of physicochemical parameters and environmental health implications. International Journal of Advanced Science and Research, Volume 9, Issue 1, 2024, Page No. 19-24.
- Aditi Tiwari, Abhishek Soni, Shalini Tiwari, Samrah Rehan, and Manisha Shukla. Assessment of water quality in a dam and downstream river following treatment. International Journal of Biotechnology and Microbiology, Volume 6, Issue 2, 2024, Page No. 17-21.
- Sonali Shrivastav, Akshita Shrivastav, Jagrati Chaturvedi, Kiran Singh and Manisha Shukla. Assessment of physical and chemical characteristics of Johila River dam water. International Journal of Environmental and Ecology Research. Volume 6, Issue 1, 2024, Page No. 13-16.
- Manisha Shukla, Pratishtha Tiwari and Sandeep Purohit. Opportunistic Fungal Urinary Tract Infection: A Case Report. World Journal of Pharmaceutical and Medical Research. 2023, 9(10), 267-270.
- Ruchi Kumari, Manisha Shukla. Sickle Cell Anaemia: Case Presentations from the Indian Tribal Population and Discussion on the Clinicopathologic Aspects. International Journal of Current Microbiology and Applied Sciences. 2023, 12(9) 67-79.
- Neha Chauhan, Prakash Narayan, Mahesh Narayan and Manisha Shukla. Case Report of a Child with Beta Thalassemia Major in a Tribal Region of India. J Child Adult Vaccines Immunol. 2023, 7, 5-7.
- Sharma, S. K., Dash, P. K., Yadav, R. G., Shrivastava, A., Menon, R., Kumar, J. S., Sharma, S., Dhankher, S., Dhiman, S., Kumari, D., Shukla, M., Relhan, V., Kumar, S., & Parida, M. (2023). Isolation and characterization of emerging Mpox virus from India. Journal of medical virology, 95(7), e28911. https://doi.org/10.1002/jmv.28911. Impact factor: 20.69
- Shukla M et al. P120 Vaccine induced protection by secreted aspartyl proteinase 2 from Candida parapsilosis in Candida tropicalis mediated murine systemic candidiasis: a role of B-cells and antibodies. Medical Mycology vol. 60, Suppl 1 myac072P120. 20 Sep. 2022. Impact factor: 3.747
- Shukla M et al. P394 Evaluation of diagnostic potential of recombinant secretory aspartyl proteinase 2 (Sap2) protein from Candida parapsilosis for use in systemic candidiasis, Medical Mycology vol 60, Suppl 1, myac072P394. Sep. 2022. Impact factor
: 3.747 - Shukla M et al. Expression, Purification, and Refolding of Chikungunya Virus Full-Length Envelope E2 Protein along with B‑Cell and T‑Cell Epitope Analyses Using Immuno-Informatics Approaches. ACS Omega. 2022, 1c05975. Impact factor: 4.132
- Shukla M et al. The Role of B-Cells and Antibodies against Candida Vaccine Antigens in Invasive Candidiasis. Vaccines. 2021 Oct;9(10):1159. Impact factor: 3.641
- Shukla M et al. Expression and purification along with evaluation of serological response and diagnostic potential of recombinant Sap2 protein from parapsilosis for use in systemic candidiasis. Journal of Fungi. 2021, 7 (12), 999. Impact factor: 5.724
- Shukla M. et al. Vaccination with secreted aspartyl proteinase 2 protein from Candida parapsilosis can enhance survival of mice during Candida tropicalis mediated systemic candidiasis. Infection and Immunity. 2020 Sep 18;88 (10):e00312-20. Impact factor: 3.441
Paper presented in Conferences/Seminars
- Presented poster in the international conference on Health, Environment and Industrial Biotechnology (Biosangam 2013), held at Motilal Nehru National Institute of Technology Allahabad, India, from 21-23 November 2013.
- Presented Poster Abstract “Investigating the protective potential of candidate vaccine antigens in murine systemic candidiasis caused by non-albicans Candida species” at Immunocon, (IIS) held at THSTI, Faridabad, 1st to 3rd Nov 2018.
- Presented Poster Abstract “Protective role of secreted aspartyl proteinase in murine systemic candidiasis caused by non-albicans Candida species” at American Association of Immunology Meeting, AAI 2019, held in San Diego, USA from 9th to 13th May 2019.
- Presented Poster Abstract “Secreted aspartyl proteinase 2 protein from Candida parapsilosis protects mice against systemic candidiasis caused by Candida tropicalis” at SIHAM (Society for Indian Human and Animal Mycologists), held at Jodhpur, India from 12th to 15th May 2020.
- Presented Poster Abstract “A role of B-cells and antibodies in generation of protective immune responses against a vaccinating antigen during non-albicans Candida mediated systemic candidiasis” at American Association of Immunology, Virtual Immunology 2021 from 10th May to 15th May 2021.
- Lecture delivered at the 8th International Conference on Human Genetics and Genetic Disorders, held during March 21, 2023 at Paris, France.
- Oral presentation on “Assessing the Prognostic Value of NLR and PLR in Sickle Cell Anemia Patients” at International Conference on Applied Research in Engineering Sciences ICAMES 2023, to be held from 7-8 December 2023 at Ramaiah Institute of Technology Bengaluru.
Invited Talks
- Lecture delivered at the 7th International Conference on Human Genetics and Genetic Disorders, held during March 21, 2023 at Paris, France.
- Lecture delivered on the topic of Sickle Cell Anemia during National Science Day Celebration by the department of computer Science, Pandit S.N. Shukla University Shahdol, Madhya Pradesh, Sponsored by MPCST, Bhopal on 27th Feb to 1st March 2023.
- Delivered lecture on “Machine Learning based Diagnosis in Pediatric Patients with Sickle Cell Anemia” @ 12th IEEE International conference on Communication System and Network Technologies on 8th April 2023. (8th and 9th of April 2023 at Technocrats Institute of Technology (Excellence) Bhopal, India.
- Delivered lecture on “Land Restoration, Desertification and Drought Resilience” during Environmental day celebration at Madhya Pradesh Pollution Control Board Regional Office Shahdol on 5th June 2024.
- Delivered lecture on “Environmental Impact of Plaster of Paris Idols: Threats to Aquatic Ecosystems and Sustainable Alternatives” at ideas for LiFE Mission (Shri Ganeshji and Durgaji ki Murti Nirmana and Visarjan hetu JanJatiya Karyashala) by Madhya Pradesh Pollution Control Board Regional Office Shahdol on 4th September 2024. (Invited as Chief guest)
Organized Symposium/Webinar/Conference
- Part of successfully organising international conference on Health, Environment and Industrial Biotechnology (Biosangam 2013), held at Motilal Nehru National Institute of Technology Allahabad, India, from 21-23 November 2013.
- Part of successfully organising Virtual Symposium on “Covid-19 Immunology”, 29 April 2021, at IIT Roorkee, Uttarakhand, India.
- Part of organising a CEP Course event, scheduled from 26.09.2022 to 30.09.2022 Defence Research Development Establishment (DRDE) Jhansi Road, Gwalior-474002, Madhya Pradesh, India.
- Member of Organizing committee of STUDENT INNOVATION FESTIVAL (SIF), India International Science Festival (IISF) at Maulana Azad National Institute of Technology (MANIT) Bhopal from 21 January 2023 to 24 January 2023, organized by Ministry of Science & technology, Government of India.
- Organised Two days International Hybrid Webinar on World Sickle Cell Anemia Day 2023 at Pandit S.N. Shukla University Shahdol Madhya Pradesh from 19 June to 20 June 2023. Theme: Sickle Cell Anemia.
- Organised Student Induction Program 2023-2024 at Pandit S.N. Shukla University Shahdol Madhya Pradesh from 01 August to 20 June 2023.
- Organised Student Induction Program 2024-2025 at Pandit S.N. Shukla University Shahdol Madhya Pradesh from 01 July to 02 July 2024.